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Cannabis compounds and their effects on you

The ensemble effect, also known as the entourage effect, is a phenomenon in which the various components of cannabis work together to produce a greater overall effect on the body. This includes not only the psychoactive compound THC, but also the non-psychoactive compounds CBD and terpenes.


The concept of the ensemble effect was first proposed in 1998 by Israeli researcher Raphael Mechoulam, who noticed that THC seemed to be more effective when used in combination with other compounds found in the cannabis plant. This led to the idea that the various components of the plant might work together in a synergistic manner to produce a greater overall effect.


One of the ways in which the ensemble effect may occur is through the interaction between THC and CBD. While THC is known for its psychoactive effects, CBD is a non-psychoactive compound that has been shown to have a range of potential therapeutic benefits. When THC and CBD are used together, they work to balance each other out and reduce the psychoactive effects of THC. This is known as the "cannabis synergy" or the "THC/CBD balance."


In addition to THC and CBD, cannabis also contains a wide range of terpenes, which are aromatic compounds that give the plant its distinct smell and flavor. These terpenes also play a role in the ensemble effect, as they have been shown to interact with the endocannabinoid system in the body and have therapeutic effects on their own.


For example, the terpene myrcene has been shown to increase the permeability of the blood-brain barrier, which may enhance the psychoactive effects of THC. Similarly, the terpene limonene has been shown to have antidepressant and anxiolytic effects, while the terpene linalool has been shown to have sedative and anxiety-reducing effects.


Top quality dispensaries will have their strains tested for each compound and its corresponding level. The next time your in your favorite shop ask to see the test results.  A knowledgeable bud tender can help guide you in the correct direction for your desired effects. Then when you consume your cannabis be cognizant of how it makes you feel, both mentally and physically.  Does it make you more creative? Does it provide pain relief or stress mitigation? Do you get sleepy, hungry, happy, horny, or energized? Keep a note of what strains give you the most desirable effects and figure out what ratios of each compounds are in it.  Then you can find other strains that have similar compound ratios.


Overall, the ensemble effect is a complex phenomenon that is still not fully understood. However, it is clear that the various components of cannabis interact with each other and the human body in a way that can produce a range of therapeutic effects. As research continues to uncover more about the ensemble effect and the role of each individual component of cannabis, it may be possible to develop more targeted and effective therapies for a variety of conditions.


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